Cargando…
Improving CRISPR-Cas nuclease specificity using truncated guide RNAs
Autores principales: | Fu, Yanfang, Sander, Jeffry D., Reyon, Deepak, Cascio, Vincent M., Joung, J. Keith |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3988262/ https://www.ncbi.nlm.nih.gov/pubmed/24463574 http://dx.doi.org/10.1038/nbt.2808 |
Ejemplares similares
-
High frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells
por: Fu, Yanfang, et al.
Publicado: (2013) -
Efficient In Vivo Genome Editing Using RNA-Guided Nucleases
por: Hwang, Woong Y., et al.
Publicado: (2013) -
Broad Specificity Profiling of TALENs Results in Engineered Nucleases With Improved DNA Cleavage Specificity
por: Guilinger, John P., et al.
Publicado: (2014) -
Heritable and Precise Zebrafish Genome Editing Using a CRISPR-Cas System
por: Hwang, Woong Y., et al.
Publicado: (2013) -
Dimeric CRISPR RNA-guided FokI nucleases for highly specific genome editing
por: Tsai, Shengdar Q., et al.
Publicado: (2014)