ASK1 promotes the contact hypersensitivity response through IL-17 production

Contact hypersensitivity (CHS) is a form of delayed-type hypersensitivity triggered by the response to reactive haptens (sensitization) and subsequent challenge (elicitation). Here, we show that ASK1 promotes CHS and that suppression of ASK1 during the elicitation phase is sufficient to attenuate CH...

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Detalles Bibliográficos
Autores principales: Mizukami, Junya, Sato, Takehiro, Camps, Montserrat, Ji, Hong, Rueckle, Thomas, Swinnen, Dominique, Tsuboi, Ryoji, Takeda, Kohsuke, Ichijo, Hidenori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3988482/
https://www.ncbi.nlm.nih.gov/pubmed/24736726
http://dx.doi.org/10.1038/srep04714

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3988482/
https://www.ncbi.nlm.nih.gov/pubmed/24736726
http://dx.doi.org/10.1038/srep04714

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