Cargando…
ASK1 promotes the contact hypersensitivity response through IL-17 production
Contact hypersensitivity (CHS) is a form of delayed-type hypersensitivity triggered by the response to reactive haptens (sensitization) and subsequent challenge (elicitation). Here, we show that ASK1 promotes CHS and that suppression of ASK1 during the elicitation phase is sufficient to attenuate CH...
Autores principales: | Mizukami, Junya, Sato, Takehiro, Camps, Montserrat, Ji, Hong, Rueckle, Thomas, Swinnen, Dominique, Tsuboi, Ryoji, Takeda, Kohsuke, Ichijo, Hidenori |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3988482/ https://www.ncbi.nlm.nih.gov/pubmed/24736726 http://dx.doi.org/10.1038/srep04714 |
Ejemplares similares
-
Therapeutic targets in the ASK1-dependent stress signaling
pathways
por: HAYAKAWA, Ryoichi, et al.
Publicado: (2012) -
ASK1 signalling regulates brown and beige adipocyte function
por: Hattori, Kazuki, et al.
Publicado: (2016) -
ASK1 signaling regulates phase-specific glial interactions during neuroinflammation
por: Guo, Xiaoli, et al.
Publicado: (2022) -
ASK1 suppresses NK cell‐mediated intravascular tumor cell clearance in lung metastasis
por: Fujimoto, Makoto, et al.
Publicado: (2021) -
ASK1-dependent recruitment and activation of macrophages induce hair growth in skin wounds
por: Osaka, Nao, et al.
Publicado: (2007)