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Mod-seq: high-throughput sequencing for chemical probing of RNA structure

The functions of RNA molecules are intimately linked to their ability to fold into complex secondary and tertiary structures. Thus, understanding how these molecules fold is essential to determining how they function. Current methods for investigating RNA structure often use small molecules, enzymes...

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Detalles Bibliográficos
Autores principales: Talkish, Jason, May, Gemma, Lin, Yizhu, Woolford, John L., McManus, C. Joel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3988572/
https://www.ncbi.nlm.nih.gov/pubmed/24664469
http://dx.doi.org/10.1261/rna.042218.113