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Fusion-Expressed CTB Improves Both Systemic and Mucosal T-Cell Responses Elicited by an Intranasal DNA Priming/Intramuscular Recombinant Vaccinia Boosting Regimen

Previous study showed that CTB (Cholera toxin subunit B) can be used as a genetic adjuvant to enhance the systemic immune responses. To further investigate whether it can also be used as a genetic adjuvant to improve mucosal immune responses, we constructed DNA and recombinant Tiantan vaccinia (rTTV...

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Detalles Bibliográficos
Autores principales:	Qiu, Sugan, Ren, Xiaonan, Ben, Yinyin, Ren, Yanqin, Wang, Jing, Zhang, Xiaoyan, Wan, Yanmin, Xu, Jianqing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3988707/ https://www.ncbi.nlm.nih.gov/pubmed/24741585 http://dx.doi.org/10.1155/2014/308732

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