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Rapamycin Regulates iTreg Function through CD39 and Runx1 Pathways

It has been shown that rapamycin is able to significantly increase the expression of FoxP3 and suppress activity in induced Treg (iTreg) cells in vivo and in vitro. CD39 is a newly determined Treg marker that relates to cell suppression. Runx1, a regulator of FoxP3, controls the expression of adenos...

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Detalles Bibliográficos
Autores principales:	Lu, Yunjie, Wang, Jirong, Gu, Jian, Lu, Hao, Li, Xiangcheng, Qian, Xiaofeng, Liu, Xiaoshan, Wang, Xuehao, Zhang, Feng, Lu, Ling
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3988749/ https://www.ncbi.nlm.nih.gov/pubmed/24741640 http://dx.doi.org/10.1155/2014/989434

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