Various applications of TALEN- and CRISPR/Cas9-mediated homologous recombination to modify the Drosophila genome

Modifying the genomes of many organisms is becoming as easy as manipulating DNA in test tubes, which is made possible by two recently developed techniques based on either the customizable DNA binding protein, TALEN, or the CRISPR/Cas9 system. Here, we describe a series of efficient applications deri...

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Detalles Bibliográficos
Autores principales: Yu, Zhongsheng, Chen, Hanqing, Liu, Jiyong, Zhang, Hongtao, Yan, Yan, Zhu, Nannan, Guo, Yawen, Yang, Bo, Chang, Yan, Dai, Fei, Liang, Xuehong, Chen, Yixu, Shen, Yan, Deng, Wu-Min, Chen, Jianming, Zhang, Bo, Li, Changqing, Jiao, Renjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3988796/
https://www.ncbi.nlm.nih.gov/pubmed/24659249
http://dx.doi.org/10.1242/bio.20147682

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