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Whisker barrel cortex delta oscillations and gamma power in the awake mouse are linked to respiration

Current evidence suggests that delta oscillations (0.5–4 Hz) in the brain are generated by intrinsic network mechanisms involving cortical and thalamic circuits. Here we report that delta band oscillation in spike and local field potential (LFP) activity in the whisker barrel cortex of awake mice is...

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Autores principales: Ito, J., Roy, S., Liu, Y., Cao, Y., Fletcher, M., Lu, L., Boughter, J.D., Grün, S., Heck, D.H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3988824/
https://www.ncbi.nlm.nih.gov/pubmed/24686563
http://dx.doi.org/10.1038/ncomms4572
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author Ito, J.
Roy, S.
Liu, Y.
Cao, Y.
Fletcher, M.
Lu, L.
Boughter, J.D.
Grün, S.
Heck, D.H.
author_facet Ito, J.
Roy, S.
Liu, Y.
Cao, Y.
Fletcher, M.
Lu, L.
Boughter, J.D.
Grün, S.
Heck, D.H.
author_sort Ito, J.
collection PubMed
description Current evidence suggests that delta oscillations (0.5–4 Hz) in the brain are generated by intrinsic network mechanisms involving cortical and thalamic circuits. Here we report that delta band oscillation in spike and local field potential (LFP) activity in the whisker barrel cortex of awake mice is phase locked to respiration. Furthermore, LFP oscillations in the gamma frequency band (30–80 Hz) are amplitude modulated in phase with the respiratory rhythm. Removal of the olfactory bulb eliminates respiration-locked delta oscillations and delta-gamma phase-amplitude coupling. Our findings thus suggest respiration-locked olfactory bulb activity as a main driving force behind delta oscillations and gamma power modulation in the whisker barrel cortex in the awake state.
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spelling pubmed-39888242014-04-18 Whisker barrel cortex delta oscillations and gamma power in the awake mouse are linked to respiration Ito, J. Roy, S. Liu, Y. Cao, Y. Fletcher, M. Lu, L. Boughter, J.D. Grün, S. Heck, D.H. Nat Commun Article Current evidence suggests that delta oscillations (0.5–4 Hz) in the brain are generated by intrinsic network mechanisms involving cortical and thalamic circuits. Here we report that delta band oscillation in spike and local field potential (LFP) activity in the whisker barrel cortex of awake mice is phase locked to respiration. Furthermore, LFP oscillations in the gamma frequency band (30–80 Hz) are amplitude modulated in phase with the respiratory rhythm. Removal of the olfactory bulb eliminates respiration-locked delta oscillations and delta-gamma phase-amplitude coupling. Our findings thus suggest respiration-locked olfactory bulb activity as a main driving force behind delta oscillations and gamma power modulation in the whisker barrel cortex in the awake state. Nature Pub. Group 2014-04-01 /pmc/articles/PMC3988824/ /pubmed/24686563 http://dx.doi.org/10.1038/ncomms4572 Text en Copyright © 2014, Nature Publishing Group, a division of Macmillan Publishers Limited. All Rights Reserved. http://creativecommons.org/licenses/by-nc-sa/3.0/ This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 3.0 Unported License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-sa/3.0/
spellingShingle Article
Ito, J.
Roy, S.
Liu, Y.
Cao, Y.
Fletcher, M.
Lu, L.
Boughter, J.D.
Grün, S.
Heck, D.H.
Whisker barrel cortex delta oscillations and gamma power in the awake mouse are linked to respiration
title Whisker barrel cortex delta oscillations and gamma power in the awake mouse are linked to respiration
title_full Whisker barrel cortex delta oscillations and gamma power in the awake mouse are linked to respiration
title_fullStr Whisker barrel cortex delta oscillations and gamma power in the awake mouse are linked to respiration
title_full_unstemmed Whisker barrel cortex delta oscillations and gamma power in the awake mouse are linked to respiration
title_short Whisker barrel cortex delta oscillations and gamma power in the awake mouse are linked to respiration
title_sort whisker barrel cortex delta oscillations and gamma power in the awake mouse are linked to respiration
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3988824/
https://www.ncbi.nlm.nih.gov/pubmed/24686563
http://dx.doi.org/10.1038/ncomms4572
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