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The Folding of a Family of Three-Helix Bundle Proteins: Spectrin R15 Has a Robust Folding Nucleus, Unlike Its Homologous Neighbours()
Three homologous spectrin domains have remarkably different folding characteristics. We have previously shown that the slow-folding R16 and R17 spectrin domains can be altered to resemble the fast folding R15, in terms of speed of folding (and unfolding), landscape roughness and folding mechanism, s...
Autores principales: | Kwa, Lee Gyan, Wensley, Beth G., Alexander, Crispin G., Browning, Stuart J., Lichman, Benjamin R., Clarke, Jane |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3988883/ https://www.ncbi.nlm.nih.gov/pubmed/24373753 http://dx.doi.org/10.1016/j.jmb.2013.12.018 |
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