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The Breast Cancer Oncogene EMSY Represses Transcription of Antimetastatic microRNA miR-31
Amplification of the EMSY gene in sporadic breast and ovarian cancers is a poor prognostic indicator. Although EMSY has been linked to transcriptional silencing, its mechanism of action is unknown. Here, we report that EMSY acts as an oncogene, causing the transformation of cells in vitro and potent...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3988886/ https://www.ncbi.nlm.nih.gov/pubmed/24582497 http://dx.doi.org/10.1016/j.molcel.2014.01.029 |
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por Viré, Emmanuelle, Curtis, Christina, Davalos, Veronica, Git, Anna, Robson, Samuel, Villanueva, Alberto, Vidal, August, Barbieri, Isaia, Aparicio, Samuel, Esteller, Manel, Caldas, Carlos, Kouzarides, Tony
Publicado 2014
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Publicado 2014
Enlace del recurso
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Online
Artículo
Texto