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Practical Guidelines: Lung Transplantation in Patients with Cystic Fibrosis
There are no European recommendations on issues specifically related to lung transplantation (LTX) in cystic fibrosis (CF). The main goal of this paper is to provide CF care team members with clinically relevant CF-specific information on all aspects of LTX, highlighting areas of consensus and contr...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3988894/ https://www.ncbi.nlm.nih.gov/pubmed/24800072 http://dx.doi.org/10.1155/2014/621342 |
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author | Hirche, T. O. Knoop, C. Hebestreit, H. Shimmin, D. Solé, A. Elborn, J. S. Ellemunter, H. Aurora, P. Hogardt, M. Wagner, T. O. F. ECORN-CF Study Group, |
author_facet | Hirche, T. O. Knoop, C. Hebestreit, H. Shimmin, D. Solé, A. Elborn, J. S. Ellemunter, H. Aurora, P. Hogardt, M. Wagner, T. O. F. ECORN-CF Study Group, |
author_sort | Hirche, T. O. |
collection | PubMed |
description | There are no European recommendations on issues specifically related to lung transplantation (LTX) in cystic fibrosis (CF). The main goal of this paper is to provide CF care team members with clinically relevant CF-specific information on all aspects of LTX, highlighting areas of consensus and controversy throughout Europe. Bilateral lung transplantation has been shown to be an important therapeutic option for end-stage CF pulmonary disease. Transplant function and patient survival after transplantation are better than in most other indications for this procedure. Attention though has to be paid to pretransplant morbidity, time for referral, evaluation, indication, and contraindication in children and in adults. This review makes extensive use of specific evidence in the field of lung transplantation in CF patients and addresses all issues of practical importance. The requirements of pre-, peri-, and postoperative management are discussed in detail including bridging to transplant and postoperative complications, immune suppression, chronic allograft dysfunction, infection, and malignancies being the most important. Among the contributors to this guiding information are 19 members of the ECORN-CF project and other experts. The document is endorsed by the European Cystic Fibrosis Society and sponsored by the Christiane Herzog Foundation. |
format | Online Article Text |
id | pubmed-3988894 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-39888942014-05-05 Practical Guidelines: Lung Transplantation in Patients with Cystic Fibrosis Hirche, T. O. Knoop, C. Hebestreit, H. Shimmin, D. Solé, A. Elborn, J. S. Ellemunter, H. Aurora, P. Hogardt, M. Wagner, T. O. F. ECORN-CF Study Group, Pulm Med Review Article There are no European recommendations on issues specifically related to lung transplantation (LTX) in cystic fibrosis (CF). The main goal of this paper is to provide CF care team members with clinically relevant CF-specific information on all aspects of LTX, highlighting areas of consensus and controversy throughout Europe. Bilateral lung transplantation has been shown to be an important therapeutic option for end-stage CF pulmonary disease. Transplant function and patient survival after transplantation are better than in most other indications for this procedure. Attention though has to be paid to pretransplant morbidity, time for referral, evaluation, indication, and contraindication in children and in adults. This review makes extensive use of specific evidence in the field of lung transplantation in CF patients and addresses all issues of practical importance. The requirements of pre-, peri-, and postoperative management are discussed in detail including bridging to transplant and postoperative complications, immune suppression, chronic allograft dysfunction, infection, and malignancies being the most important. Among the contributors to this guiding information are 19 members of the ECORN-CF project and other experts. The document is endorsed by the European Cystic Fibrosis Society and sponsored by the Christiane Herzog Foundation. Hindawi Publishing Corporation 2014 2014-03-30 /pmc/articles/PMC3988894/ /pubmed/24800072 http://dx.doi.org/10.1155/2014/621342 Text en Copyright © 2014 T. O. Hirche et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Hirche, T. O. Knoop, C. Hebestreit, H. Shimmin, D. Solé, A. Elborn, J. S. Ellemunter, H. Aurora, P. Hogardt, M. Wagner, T. O. F. ECORN-CF Study Group, Practical Guidelines: Lung Transplantation in Patients with Cystic Fibrosis |
title | Practical Guidelines: Lung Transplantation in Patients with Cystic Fibrosis |
title_full | Practical Guidelines: Lung Transplantation in Patients with Cystic Fibrosis |
title_fullStr | Practical Guidelines: Lung Transplantation in Patients with Cystic Fibrosis |
title_full_unstemmed | Practical Guidelines: Lung Transplantation in Patients with Cystic Fibrosis |
title_short | Practical Guidelines: Lung Transplantation in Patients with Cystic Fibrosis |
title_sort | practical guidelines: lung transplantation in patients with cystic fibrosis |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3988894/ https://www.ncbi.nlm.nih.gov/pubmed/24800072 http://dx.doi.org/10.1155/2014/621342 |
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