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Insights into TREM2 biology by network analysis of human brain gene expression data
Rare variants in TREM2 cause susceptibility to late-onset Alzheimer's disease. Here we use microarray-based expression data generated from 101 neuropathologically normal individuals and covering 10 brain regions, including the hippocampus, to understand TREM2 biology in human brain. Using netwo...
Autores principales: | Forabosco, Paola, Ramasamy, Adaikalavan, Trabzuni, Daniah, Walker, Robert, Smith, Colin, Bras, Jose, Levine, Adam P., Hardy, John, Pocock, Jennifer M., Guerreiro, Rita, Weale, Michael E., Ryten, Mina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3988951/ https://www.ncbi.nlm.nih.gov/pubmed/23855984 http://dx.doi.org/10.1016/j.neurobiolaging.2013.05.001 |
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