Cargando…
Tumour heterogeneity and immune-modulation
Recent advances in sequencing technologies have revealed extensive intratumour heterogeneity (ITH) both within individual tumours and between primary and metastatic tumours for different cancer types. Such genetic diversity may have clinical implications for both cancer diagnosis and treatment with...
Autores principales: | Jamal-Hanjani, Mariam, Thanopoulou, Eirini, Peggs, Karl S, Quezada, Sergio A, Swanton, Charles |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Science Ltd
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3988963/ https://www.ncbi.nlm.nih.gov/pubmed/23664091 http://dx.doi.org/10.1016/j.coph.2013.04.006 |
Ejemplares similares
-
The role of tumour heterogeneity and clonal cooperativity in metastasis, immune evasion and clinical outcome
por: Caswell, Deborah R., et al.
Publicado: (2017) -
Delivering preventive, predictive and personalised cancer medicine for renal cell carcinoma: the challenge of tumour heterogeneity
por: Fisher, Rosalie, et al.
Publicado: (2011) -
Quantification of tumour evolution and heterogeneity via Bayesian epiallele detection
por: Barrett, James E., et al.
Publicado: (2017) -
Ultra-deep T cell receptor sequencing reveals the complexity and intratumour heterogeneity of T cell clones in renal cell carcinomas
por: Gerlinger, Marco, et al.
Publicado: (2013) -
Exploiting CTLA-4, PD-1 and PD-L1 to reactivate the host immune response against cancer
por: Quezada, S A, et al.
Publicado: (2013)