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Kaleidoscopic protein–protein interactions in the life and death of ataxin-1: new strategies against protein aggregation()
Understanding how proteins protect themselves from aberrant aggregation is of primary interest for understanding basic biology, protein biochemistry, and human disease. We discuss the paradigmatic example of ataxin-1 (Atx1), the protein responsible for neurodegenerative spinocerebellar ataxia type 1...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Elsevier Applied Science Publishing
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3988977/ https://www.ncbi.nlm.nih.gov/pubmed/24636457 http://dx.doi.org/10.1016/j.tins.2014.02.003 |