Mapping the Genetic Architecture of Gene Regulation in Whole Blood

BACKGROUND: We aimed to assess whether whole blood expression quantitative trait loci (eQTLs) with effects in cis and trans are robust and can be used to identify regulatory pathways affecting disease susceptibility. MATERIALS AND METHODS: We performed whole-genome eQTL analyses in 890 participants...

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Detalles Bibliográficos
Autores principales: Schramm, Katharina, Marzi, Carola, Schurmann, Claudia, Carstensen, Maren, Reinmaa, Eva, Biffar, Reiner, Eckstein, Gertrud, Gieger, Christian, Grabe, Hans-Jörgen, Homuth, Georg, Kastenmüller, Gabriele, Mägi, Reedik, Metspalu, Andres, Mihailov, Evelin, Peters, Annette, Petersmann, Astrid, Roden, Michael, Strauch, Konstantin, Suhre, Karsten, Teumer, Alexander, Völker, Uwe, Völzke, Henry, Wang-Sattler, Rui, Waldenberger, Melanie, Meitinger, Thomas, Illig, Thomas, Herder, Christian, Grallert, Harald, Prokisch, Holger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3989189/
https://www.ncbi.nlm.nih.gov/pubmed/24740359
http://dx.doi.org/10.1371/journal.pone.0093844

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