A Novel Carbonyl Reductase with Anti-Prelog Stereospecificity from Acetobacter sp. CCTCC M209061: Purification and Characterization

A novel carbonyl reductase (AcCR) catalyzing the asymmetric reduction of ketones to enantiopure alcohols with anti-Prelog stereoselectivity was found in Acetobacter sp. CCTCC M209061 and enriched 27.5-fold with an overall yield of 0.4% by purification. The enzyme showed a homotetrameric structure wi...

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Detalles Bibliográficos
Autores principales: Chen, Xiao-Hong, Wei, Ping, Wang, Xiao-Ting, Zong, Min-Hua, Lou, Wen-Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3989197/
https://www.ncbi.nlm.nih.gov/pubmed/24740089
http://dx.doi.org/10.1371/journal.pone.0094543

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3989197/
https://www.ncbi.nlm.nih.gov/pubmed/24740089
http://dx.doi.org/10.1371/journal.pone.0094543

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