Interleukin-7 and Toll-Like Receptor 7 Induce Synergistic B Cell and T Cell Activation

OBJECTIVES: To investigate the potential synergy of IL-7-driven T cell-dependent and TLR7-mediated B cell activation and to assess the additive effects of monocyte/macrophages in this respect. METHODS: Isolated CD19 B cells and CD4 T cells from healthy donors were co-cultured with TLR7 agonist (TLR7...

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Detalles Bibliográficos
Autores principales: Bikker, Angela, Kruize, Aike A., van der Wurff-Jacobs, Kim M. G., Peters, Rogier P., Kleinjan, Marije, Redegeld, Frank, de Jager, Wilco, Lafeber, Floris P. J. G., van Roon, Joël A. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3989236/
https://www.ncbi.nlm.nih.gov/pubmed/24740301
http://dx.doi.org/10.1371/journal.pone.0094756

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3989236/
https://www.ncbi.nlm.nih.gov/pubmed/24740301
http://dx.doi.org/10.1371/journal.pone.0094756

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