Cargando…

An Investigation of Outpatient Children's Blood Lead Level in Wuhan China

OBJECTIVE: Blood lead levels (BLLs) and possible influencing factors in children in Wuhan China were investigated in order to understand current lead pollution exposure and provide a scientific basis for prevention and policy making. MATERIALS AND METHODS: BLL data were collected from 15,536 out-pat...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Ying, Wu, Siqi, Xiang, Yun, Liang, Xiaohui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3989303/
https://www.ncbi.nlm.nih.gov/pubmed/24740029
http://dx.doi.org/10.1371/journal.pone.0095284
_version_ 1782312145043587072
author Li, Ying
Wu, Siqi
Xiang, Yun
Liang, Xiaohui
author_facet Li, Ying
Wu, Siqi
Xiang, Yun
Liang, Xiaohui
author_sort Li, Ying
collection PubMed
description OBJECTIVE: Blood lead levels (BLLs) and possible influencing factors in children in Wuhan China were investigated in order to understand current lead pollution exposure and provide a scientific basis for prevention and policy making. MATERIALS AND METHODS: BLL data were collected from 15,536 out-patients in Wuhan Children Hospital in 2012 full year. All of them were under 18 years of age (Mean ± SD: 4.32±3.2, 64.4% boys). The BLLs were measured by an atomic absorption spectrometry (BH2100). RESULTS: The geometric mean of BLLs for all the subjects was 44.75 µg/L (95%CI: 44.46 µg/L – 45.05 µg/L), much lower than that reported in previous studies. The prevalence of the elevated BLLs (≥ 100 µg/L) in the children tested was 2% in 2012 and the prevalence of BLLs (≥ 50 µg/L) was 44%. Age and sex could be possible influencing factors for BLLs in the children (p<0.001). In addition, the BLLs in different seasons were different (p<0.001). CONCLUSIONS: These results demonstrate that BLLs have significantly decreased in children in Wuhan during recent years. However, we should continuously pay attention to lead pollution and emphasize that prevention is much more important than treatment for controlling children's BLLs.
format Online
Article
Text
id pubmed-3989303
institution National Center for Biotechnology Information
language English
publishDate 2014
publisher Public Library of Science
record_format MEDLINE/PubMed
spelling pubmed-39893032014-04-21 An Investigation of Outpatient Children's Blood Lead Level in Wuhan China Li, Ying Wu, Siqi Xiang, Yun Liang, Xiaohui PLoS One Research Article OBJECTIVE: Blood lead levels (BLLs) and possible influencing factors in children in Wuhan China were investigated in order to understand current lead pollution exposure and provide a scientific basis for prevention and policy making. MATERIALS AND METHODS: BLL data were collected from 15,536 out-patients in Wuhan Children Hospital in 2012 full year. All of them were under 18 years of age (Mean ± SD: 4.32±3.2, 64.4% boys). The BLLs were measured by an atomic absorption spectrometry (BH2100). RESULTS: The geometric mean of BLLs for all the subjects was 44.75 µg/L (95%CI: 44.46 µg/L – 45.05 µg/L), much lower than that reported in previous studies. The prevalence of the elevated BLLs (≥ 100 µg/L) in the children tested was 2% in 2012 and the prevalence of BLLs (≥ 50 µg/L) was 44%. Age and sex could be possible influencing factors for BLLs in the children (p<0.001). In addition, the BLLs in different seasons were different (p<0.001). CONCLUSIONS: These results demonstrate that BLLs have significantly decreased in children in Wuhan during recent years. However, we should continuously pay attention to lead pollution and emphasize that prevention is much more important than treatment for controlling children's BLLs. Public Library of Science 2014-04-16 /pmc/articles/PMC3989303/ /pubmed/24740029 http://dx.doi.org/10.1371/journal.pone.0095284 Text en © 2014 Li et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research Article
Li, Ying
Wu, Siqi
Xiang, Yun
Liang, Xiaohui
An Investigation of Outpatient Children's Blood Lead Level in Wuhan China
title An Investigation of Outpatient Children's Blood Lead Level in Wuhan China
title_full An Investigation of Outpatient Children's Blood Lead Level in Wuhan China
title_fullStr An Investigation of Outpatient Children's Blood Lead Level in Wuhan China
title_full_unstemmed An Investigation of Outpatient Children's Blood Lead Level in Wuhan China
title_short An Investigation of Outpatient Children's Blood Lead Level in Wuhan China
title_sort investigation of outpatient children's blood lead level in wuhan china
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3989303/
https://www.ncbi.nlm.nih.gov/pubmed/24740029
http://dx.doi.org/10.1371/journal.pone.0095284
work_keys_str_mv AT liying aninvestigationofoutpatientchildrensbloodleadlevelinwuhanchina
AT wusiqi aninvestigationofoutpatientchildrensbloodleadlevelinwuhanchina
AT xiangyun aninvestigationofoutpatientchildrensbloodleadlevelinwuhanchina
AT liangxiaohui aninvestigationofoutpatientchildrensbloodleadlevelinwuhanchina
AT liying investigationofoutpatientchildrensbloodleadlevelinwuhanchina
AT wusiqi investigationofoutpatientchildrensbloodleadlevelinwuhanchina
AT xiangyun investigationofoutpatientchildrensbloodleadlevelinwuhanchina
AT liangxiaohui investigationofoutpatientchildrensbloodleadlevelinwuhanchina