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An Investigation of Outpatient Children's Blood Lead Level in Wuhan China
OBJECTIVE: Blood lead levels (BLLs) and possible influencing factors in children in Wuhan China were investigated in order to understand current lead pollution exposure and provide a scientific basis for prevention and policy making. MATERIALS AND METHODS: BLL data were collected from 15,536 out-pat...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3989303/ https://www.ncbi.nlm.nih.gov/pubmed/24740029 http://dx.doi.org/10.1371/journal.pone.0095284 |
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author | Li, Ying Wu, Siqi Xiang, Yun Liang, Xiaohui |
author_facet | Li, Ying Wu, Siqi Xiang, Yun Liang, Xiaohui |
author_sort | Li, Ying |
collection | PubMed |
description | OBJECTIVE: Blood lead levels (BLLs) and possible influencing factors in children in Wuhan China were investigated in order to understand current lead pollution exposure and provide a scientific basis for prevention and policy making. MATERIALS AND METHODS: BLL data were collected from 15,536 out-patients in Wuhan Children Hospital in 2012 full year. All of them were under 18 years of age (Mean ± SD: 4.32±3.2, 64.4% boys). The BLLs were measured by an atomic absorption spectrometry (BH2100). RESULTS: The geometric mean of BLLs for all the subjects was 44.75 µg/L (95%CI: 44.46 µg/L – 45.05 µg/L), much lower than that reported in previous studies. The prevalence of the elevated BLLs (≥ 100 µg/L) in the children tested was 2% in 2012 and the prevalence of BLLs (≥ 50 µg/L) was 44%. Age and sex could be possible influencing factors for BLLs in the children (p<0.001). In addition, the BLLs in different seasons were different (p<0.001). CONCLUSIONS: These results demonstrate that BLLs have significantly decreased in children in Wuhan during recent years. However, we should continuously pay attention to lead pollution and emphasize that prevention is much more important than treatment for controlling children's BLLs. |
format | Online Article Text |
id | pubmed-3989303 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-39893032014-04-21 An Investigation of Outpatient Children's Blood Lead Level in Wuhan China Li, Ying Wu, Siqi Xiang, Yun Liang, Xiaohui PLoS One Research Article OBJECTIVE: Blood lead levels (BLLs) and possible influencing factors in children in Wuhan China were investigated in order to understand current lead pollution exposure and provide a scientific basis for prevention and policy making. MATERIALS AND METHODS: BLL data were collected from 15,536 out-patients in Wuhan Children Hospital in 2012 full year. All of them were under 18 years of age (Mean ± SD: 4.32±3.2, 64.4% boys). The BLLs were measured by an atomic absorption spectrometry (BH2100). RESULTS: The geometric mean of BLLs for all the subjects was 44.75 µg/L (95%CI: 44.46 µg/L – 45.05 µg/L), much lower than that reported in previous studies. The prevalence of the elevated BLLs (≥ 100 µg/L) in the children tested was 2% in 2012 and the prevalence of BLLs (≥ 50 µg/L) was 44%. Age and sex could be possible influencing factors for BLLs in the children (p<0.001). In addition, the BLLs in different seasons were different (p<0.001). CONCLUSIONS: These results demonstrate that BLLs have significantly decreased in children in Wuhan during recent years. However, we should continuously pay attention to lead pollution and emphasize that prevention is much more important than treatment for controlling children's BLLs. Public Library of Science 2014-04-16 /pmc/articles/PMC3989303/ /pubmed/24740029 http://dx.doi.org/10.1371/journal.pone.0095284 Text en © 2014 Li et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited. |
spellingShingle | Research Article Li, Ying Wu, Siqi Xiang, Yun Liang, Xiaohui An Investigation of Outpatient Children's Blood Lead Level in Wuhan China |
title | An Investigation of Outpatient Children's Blood Lead Level in Wuhan China |
title_full | An Investigation of Outpatient Children's Blood Lead Level in Wuhan China |
title_fullStr | An Investigation of Outpatient Children's Blood Lead Level in Wuhan China |
title_full_unstemmed | An Investigation of Outpatient Children's Blood Lead Level in Wuhan China |
title_short | An Investigation of Outpatient Children's Blood Lead Level in Wuhan China |
title_sort | investigation of outpatient children's blood lead level in wuhan china |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3989303/ https://www.ncbi.nlm.nih.gov/pubmed/24740029 http://dx.doi.org/10.1371/journal.pone.0095284 |
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