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Analysis of Ultra-Deep Pyrosequencing and Cloning Based Sequencing of the Basic Core Promoter/Precore/Core Region of Hepatitis B Virus Using Newly Developed Bioinformatics Tools

AIMS: The aims of this study were to develop bioinformatics tools to explore ultra-deep pyrosequencing (UDPS) data, to test these tools, and to use them to determine the optimum error threshold, and to compare results from UDPS and cloning based sequencing (CBS). METHODS: Four serum samples, infecte...

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Detalles Bibliográficos
Autores principales: Yousif, Mukhlid, Bell, Trevor G., Mudawi, Hatim, Glebe, Dieter, Kramvis, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3989311/
https://www.ncbi.nlm.nih.gov/pubmed/24740330
http://dx.doi.org/10.1371/journal.pone.0095377

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