Enhanced Inflammatory Potential of CD4(+) T-Cells That Lack Proteasome Immunosubunit Expression, in a T-Cell Transfer-Based Colitis Model

Proteasomes play a fundamental role in intracellular protein degradation and therewith regulate a variety of cellular processes. Exposure of cells to (pro)inflammatory cytokines upregulates the expression of three inducible catalytic proteasome subunits, the immunosubunits, which incorporate into ne...

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Detalles Bibliográficos
Autores principales: Rasid, Orhan, Meulenbroeks, Chantal, Gröne, Andrea, Zaiss, Dietmar, Sijts, Alice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3989320/
https://www.ncbi.nlm.nih.gov/pubmed/24740379
http://dx.doi.org/10.1371/journal.pone.0095378

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3989320/
https://www.ncbi.nlm.nih.gov/pubmed/24740379
http://dx.doi.org/10.1371/journal.pone.0095378

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