Activity-Dependent Dendritic Spine Shrinkage and Growth Involve Downregulation of Cofilin via Distinct Mechanisms

A current model posits that cofilin-dependent actin severing negatively impacts dendritic spine volume. Studies suggested that increased cofilin activity underlies activity-dependent spine shrinkage, and that reduced cofilin activity induces activity-dependent spine growth. We suggest instead that b...

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Detalles Bibliográficos
Autores principales: Calabrese, Barbara, Saffin, Jean-Michel, Halpain, Shelley
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3989342/
https://www.ncbi.nlm.nih.gov/pubmed/24740405
http://dx.doi.org/10.1371/journal.pone.0094787

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3989342/
https://www.ncbi.nlm.nih.gov/pubmed/24740405
http://dx.doi.org/10.1371/journal.pone.0094787

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