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A Quantitative Increase in Regulatory T Cells Controls Development of Vitiligo
T cell cytolytic activity targeting epidermal melanocyte is shown to cause progressive depigmentation and autoimmune vitiligo. Using the recently developed transgenic mice h3TA2 that carry T cell with a HLA-A2 restricted human tyrosinase reactive TCR and develop spontaneous vitiligo from an early ag...
Autores principales: | Chatterjee, Shilpak, Eby, Jonathan, Al-Khami, Amir A., Soloshchenko, Myroslawa, Kang, Hee-Kap, Kaur, Navtej, Naga, Osama, Murali, Anuradha, Nishimura, Michael I., Le Poole, I. Caroline, Mehrotra, Shikhar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3989443/ https://www.ncbi.nlm.nih.gov/pubmed/24366614 http://dx.doi.org/10.1038/jid.2013.540 |
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