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Mad1 contribution to spindle assembly checkpoint signalling goes beyond presenting Mad2 at kinetochores

The spindle assembly checkpoint inhibits anaphase until all chromosomes have become attached to the mitotic spindle. A complex between the checkpoint proteins Mad1 and Mad2 provides a platform for Mad2:Mad2 dimerization at unattached kinetochores, which enables Mad2 to delay anaphase. Here, we show...

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Detalles Bibliográficos
Autores principales:	Heinrich, Stephanie, Sewart, Katharina, Windecker, Hanna, Langegger, Maria, Schmidt, Nadine, Hustedt, Nicole, Hauf, Silke
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 2014
Materias:	Scientific Reports
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3989695/ https://www.ncbi.nlm.nih.gov/pubmed/24477934 http://dx.doi.org/10.1002/embr.201338114

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