Protein Phosphatase 1 Recruitment by Rif1 Regulates DNA Replication Origin Firing by Counteracting DDK Activity

The firing of eukaryotic origins of DNA replication requires CDK and DDK kinase activities. DDK, in particular, is involved in setting the temporal program of origin activation, a conserved feature of eukaryotes. Rif1, originally identified as a telomeric protein, was recently implicated in specifyi...

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Detalles Bibliográficos
Autores principales: Davé, Anoushka, Cooley, Carol, Garg, Mansi, Bianchi, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2014
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3989773/
https://www.ncbi.nlm.nih.gov/pubmed/24656819
http://dx.doi.org/10.1016/j.celrep.2014.02.019

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