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Protein Phosphatase 1 Recruitment by Rif1 Regulates DNA Replication Origin Firing by Counteracting DDK Activity
The firing of eukaryotic origins of DNA replication requires CDK and DDK kinase activities. DDK, in particular, is involved in setting the temporal program of origin activation, a conserved feature of eukaryotes. Rif1, originally identified as a telomeric protein, was recently implicated in specifyi...
Autores principales: | Davé, Anoushka, Cooley, Carol, Garg, Mansi, Bianchi, Alessandro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3989773/ https://www.ncbi.nlm.nih.gov/pubmed/24656819 http://dx.doi.org/10.1016/j.celrep.2014.02.019 |
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