Phosphorylation-Dependent PIH1D1 Interactions Define Substrate Specificity of the R2TP Cochaperone Complex

The R2TP cochaperone complex plays a critical role in the assembly of multisubunit machines, including small nucleolar ribonucleoproteins (snoRNPs), RNA polymerase II, and the mTORC1 and SMG1 kinase complexes, but the molecular basis of substrate recognition remains unclear. Here, we describe a phos...

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Detalles Bibliográficos
Autores principales: Hořejší, Zuzana, Stach, Lasse, Flower, Thomas G., Joshi, Dhira, Flynn, Helen, Skehel, J. Mark, O’Reilly, Nicola J., Ogrodowicz, Roksana W., Smerdon, Stephen J., Boulton, Simon J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2014
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3989777/
https://www.ncbi.nlm.nih.gov/pubmed/24656813
http://dx.doi.org/10.1016/j.celrep.2014.03.013

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