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Msd1/SSX2IP-dependent microtubule anchorage ensures spindle orientation and primary cilia formation

Anchoring microtubules to the centrosome is critical for cell geometry and polarity, yet the molecular mechanism remains unknown. Here we show that the conserved human Msd1/SSX2IP is required for microtubule anchoring. hMsd1/SSX2IP is delivered to the centrosome in a centriolar satellite-dependent m...

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Detalles Bibliográficos
Autores principales: Hori, Akiko, Ikebe, Chiho, Tada, Masazumi, Toda, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3989863/
https://www.ncbi.nlm.nih.gov/pubmed/24397932
http://dx.doi.org/10.1002/embr.201337929

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