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Seroprevalence of Hepatitis A among Students Enrolled in Tehran University of Medical Sciences during 2011
BACKGROUND: Hepatitis A is often asymptomatic in children, however it can become a serious disease in adults. For countries that do not have a universal vaccination strategy targeted vaccination for high risk groups is recommended. Health workers could be at a higher risk of infection with hepatitis...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Iranian Association of Gastroerterology and Hepatology
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3990182/ https://www.ncbi.nlm.nih.gov/pubmed/24829683 |
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author | Rabiee, Anahita Nikayin, Sina Hashemi, Seyed Reza Mohaghegh, Mostafa Amini, Marzieh Rabiee, Roozbeh Merat, Shahin |
author_facet | Rabiee, Anahita Nikayin, Sina Hashemi, Seyed Reza Mohaghegh, Mostafa Amini, Marzieh Rabiee, Roozbeh Merat, Shahin |
author_sort | Rabiee, Anahita |
collection | PubMed |
description | BACKGROUND: Hepatitis A is often asymptomatic in children, however it can become a serious disease in adults. For countries that do not have a universal vaccination strategy targeted vaccination for high risk groups is recommended. Health workers could be at a higher risk of infection with hepatitis A virus (HAV) compared to the general population. The aim of this study is to investigate the seroprevalence of hepatitis A among enrolled students in Tehran University of Medical Sciences in 2011. METHODS: This study included all students enrolled in Tehran University of Medical Sciences during 2011. We checked serum samples for anti-HAV antibody and participants completed a simple questionnaire. RESULTS: From 1864 health sciences students enrolled in Tehran University of Medical Sciences, 1813 samples were analyzed for anti-HAV IgG antibody. The results showed that 970 (53.5%) were seronegative, 722 (39.8%) were seropositive, and 121 (6.7%) were equivocal. There were significantly higher seropositive results for males (54%) compared to females (37%; RR = 1.46; 95% CI: 1.31-1.62). CONCLUSION: The seroprevalence of HAV among enrolled medical science students is considerably lower than previous reports from Iran. Targeted vaccination for health sciences students prior to exposure should be seriously considered. |
format | Online Article Text |
id | pubmed-3990182 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Iranian Association of Gastroerterology and Hepatology |
record_format | MEDLINE/PubMed |
spelling | pubmed-39901822014-05-14 Seroprevalence of Hepatitis A among Students Enrolled in Tehran University of Medical Sciences during 2011 Rabiee, Anahita Nikayin, Sina Hashemi, Seyed Reza Mohaghegh, Mostafa Amini, Marzieh Rabiee, Roozbeh Merat, Shahin Middle East J Dig Dis Original Article BACKGROUND: Hepatitis A is often asymptomatic in children, however it can become a serious disease in adults. For countries that do not have a universal vaccination strategy targeted vaccination for high risk groups is recommended. Health workers could be at a higher risk of infection with hepatitis A virus (HAV) compared to the general population. The aim of this study is to investigate the seroprevalence of hepatitis A among enrolled students in Tehran University of Medical Sciences in 2011. METHODS: This study included all students enrolled in Tehran University of Medical Sciences during 2011. We checked serum samples for anti-HAV antibody and participants completed a simple questionnaire. RESULTS: From 1864 health sciences students enrolled in Tehran University of Medical Sciences, 1813 samples were analyzed for anti-HAV IgG antibody. The results showed that 970 (53.5%) were seronegative, 722 (39.8%) were seropositive, and 121 (6.7%) were equivocal. There were significantly higher seropositive results for males (54%) compared to females (37%; RR = 1.46; 95% CI: 1.31-1.62). CONCLUSION: The seroprevalence of HAV among enrolled medical science students is considerably lower than previous reports from Iran. Targeted vaccination for health sciences students prior to exposure should be seriously considered. Iranian Association of Gastroerterology and Hepatology 2013-07 /pmc/articles/PMC3990182/ /pubmed/24829683 Text en © 2013 by Middle East Journal of Digestive Diseases This work is published by Middle East Journal of Digestive Diseases as an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by-nc-sa/4.0/). Non-commercial uses of the work are permitted, provided the original work is properly cited. |
spellingShingle | Original Article Rabiee, Anahita Nikayin, Sina Hashemi, Seyed Reza Mohaghegh, Mostafa Amini, Marzieh Rabiee, Roozbeh Merat, Shahin Seroprevalence of Hepatitis A among Students Enrolled in Tehran University of Medical Sciences during 2011 |
title | Seroprevalence of Hepatitis A among Students Enrolled in Tehran University of Medical Sciences during 2011 |
title_full | Seroprevalence of Hepatitis A among Students Enrolled in Tehran University of Medical Sciences during 2011 |
title_fullStr | Seroprevalence of Hepatitis A among Students Enrolled in Tehran University of Medical Sciences during 2011 |
title_full_unstemmed | Seroprevalence of Hepatitis A among Students Enrolled in Tehran University of Medical Sciences during 2011 |
title_short | Seroprevalence of Hepatitis A among Students Enrolled in Tehran University of Medical Sciences during 2011 |
title_sort | seroprevalence of hepatitis a among students enrolled in tehran university of medical sciences during 2011 |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3990182/ https://www.ncbi.nlm.nih.gov/pubmed/24829683 |
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