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Genetic variant rs1058240 at the microRNA-binding site in the GATA3 gene may regulate its mRNA expression

The GATA binding protein 3 (GATA3) is a member of a family of 6 GATA dual zinc finger transcription factors (GATA1-6), which are required for the development and morphogenesis of the mammary gland. GATA3 is considered to play a dual role in oncogenesis and cancer development, whereas somatic GATA3 m...

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Detalles Bibliográficos
Autores principales: YANG, FANG, CHEN, FENXIA, GU, JUN, ZHANG, WENWEN, LUO, JIAYAN, GUAN, XIAOXIANG
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3990192/
https://www.ncbi.nlm.nih.gov/pubmed/24748983
http://dx.doi.org/10.3892/br.2014.254