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Genetic variant rs1058240 at the microRNA-binding site in the GATA3 gene may regulate its mRNA expression
The GATA binding protein 3 (GATA3) is a member of a family of 6 GATA dual zinc finger transcription factors (GATA1-6), which are required for the development and morphogenesis of the mammary gland. GATA3 is considered to play a dual role in oncogenesis and cancer development, whereas somatic GATA3 m...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3990192/ https://www.ncbi.nlm.nih.gov/pubmed/24748983 http://dx.doi.org/10.3892/br.2014.254 |