Nrf2 reduces levels of phosphorylated tau protein by inducing autophagy adaptor protein NDP52

Nuclear factor E2-related factor 2 (Nrf2) is a pivotal transcription factor in the defense against oxidative stress. Here we provide evidence that activation of the Nrf2 pathway reduces the levels of phosphorylated tau by induction of an autophagy adaptor protein NDP52 (also known as CALCOCO2) in ne...

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Detalles Bibliográficos
Autores principales: Jo, Chulman, Gundemir, Soner, Pritchard, Susanne, Jin, Youngnam N., Rahman, Irfan, Johnson, Gail V.W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3990284/
https://www.ncbi.nlm.nih.gov/pubmed/24667209
http://dx.doi.org/10.1038/ncomms4496

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3990284/
https://www.ncbi.nlm.nih.gov/pubmed/24667209
http://dx.doi.org/10.1038/ncomms4496

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