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Nrf2 reduces levels of phosphorylated tau protein by inducing autophagy adaptor protein NDP52
Nuclear factor E2-related factor 2 (Nrf2) is a pivotal transcription factor in the defense against oxidative stress. Here we provide evidence that activation of the Nrf2 pathway reduces the levels of phosphorylated tau by induction of an autophagy adaptor protein NDP52 (also known as CALCOCO2) in ne...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3990284/ https://www.ncbi.nlm.nih.gov/pubmed/24667209 http://dx.doi.org/10.1038/ncomms4496 |