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Mutational signatures: the patterns of somatic mutations hidden in cancer genomes()
All cancers originate from a single cell that starts to behave abnormally due to the acquired somatic mutations in its genome. Until recently, the knowledge of the mutational processes that cause these somatic mutations has been very limited. Recent advances in sequencing technologies and the develo...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3990474/ https://www.ncbi.nlm.nih.gov/pubmed/24657537 http://dx.doi.org/10.1016/j.gde.2013.11.014 |