Recombinant Paracoccin Reproduces the Biological Properties of the Native Protein and Induces Protective Th1 Immunity against Paracoccidioides brasiliensis Infection

BACKGROUND: Paracoccin is a dual-function protein of the yeast Paracoccidioides brasiliensis that has lectin properties and N-acetylglucosaminidase activities. Proteomic analysis of a paracoccin preparation from P. brasiliensis revealed that the sequence matched that of the hypothetical protein enco...

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Detalles Bibliográficos
Autores principales: Alegre, Ana Claudia Paiva, Oliveira, Aline Ferreira, Dos Reis Almeida, Fausto Bruno, Roque-Barreira, Maria Cristina, Hanna, Ebert Seixas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3990478/
https://www.ncbi.nlm.nih.gov/pubmed/24743161
http://dx.doi.org/10.1371/journal.pntd.0002788

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