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Identification of the Critical Sites of NNRTI-Resistance in Reverse Transcriptase of HIV-1 CRF_BC Strains

BACKGROUND: The polymorphisms involved in drug resistance to non-nucleoside reverse transcriptase inhibitors (NNRTIs) in HIV-1 CRF_BC, the most prevalent HIV-1 strain in China, have been poorly characterized. RESULTS: To reveal the drug resistance mutations, we compared the gene sequences of pol reg...

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Detalles Bibliográficos
Autores principales: Huang, Yang, Li, Zhenpeng, Xing, Hui, Jiao, Yang, Ouyang, Yabo, Liao, Lingjie, Jiang, Shibo, Armstrong, Rebecca, Shao, Yiming, Ma, Liying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3990534/
https://www.ncbi.nlm.nih.gov/pubmed/24743727
http://dx.doi.org/10.1371/journal.pone.0093804