Potential for Pancreatic Maturation of Differentiating Human Embryonic Stem Cells Is Sensitive to the Specific Pathway of Definitive Endoderm Commitment

This study provides a detailed experimental and mathematical analysis of the impact of the initial pathway of definitive endoderm (DE) induction on later stages of pancreatic maturation. Human embryonic stem cells (hESCs) were induced to insulin-producing cells following a directed-differentiation a...

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Detalles Bibliográficos
Autores principales: Jaramillo, Maria, Mathew, Shibin, Task, Keith, Barner, Sierra, Banerjee, Ipsita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3990550/
https://www.ncbi.nlm.nih.gov/pubmed/24743345
http://dx.doi.org/10.1371/journal.pone.0094307

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3990550/
https://www.ncbi.nlm.nih.gov/pubmed/24743345
http://dx.doi.org/10.1371/journal.pone.0094307

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