Cargando…

Potential for Pancreatic Maturation of Differentiating Human Embryonic Stem Cells Is Sensitive to the Specific Pathway of Definitive Endoderm Commitment

This study provides a detailed experimental and mathematical analysis of the impact of the initial pathway of definitive endoderm (DE) induction on later stages of pancreatic maturation. Human embryonic stem cells (hESCs) were induced to insulin-producing cells following a directed-differentiation a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jaramillo, Maria, Mathew, Shibin, Task, Keith, Barner, Sierra, Banerjee, Ipsita
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3990550/ https://www.ncbi.nlm.nih.gov/pubmed/24743345 http://dx.doi.org/10.1371/journal.pone.0094307

Ejemplares similares

Population Based Model of Human Embryonic Stem Cell (hESC) Differentiation during Endoderm Induction
por: Task, Keith, et al.
Publicado: (2012)

Analysis of alternative signaling pathways of endoderm induction of human embryonic stem cells identifies context specific differences
por: Mathew, Shibin, et al.
Publicado: (2012)

Stauprimide Priming of Human Embryonic Stem Cells toward Definitive Endoderm
por: Tahamtani, Yaser, et al.
Publicado: (2014)

Early differentiation patterning of mouse embryonic stem cells in response to variations in alginate substrate stiffness
por: Candiello, Joseph, et al.
Publicado: (2013)

Collagen Type I Improves the Differentiation of Human Embryonic Stem Cells towards Definitive Endoderm
por: Rasmussen, Camilla Holzmann, et al.
Publicado: (2015)

Human Embryonic and Rat Adult Stem Cells with Primitive Endoderm-Like Phenotype Can Be Fated to Definitive Endoderm, and Finally Hepatocyte-Like Cells
por: Roelandt, Philip, et al.
Publicado: (2010)

Single-cell RNA-seq reveals novel regulators of human embryonic stem cell differentiation to definitive endoderm
por: Chu, Li-Fang, et al.
Publicado: (2016)

Epigenetic Induction of Definitive and Pancreatic Endoderm Cell Fate in Human Fibroblasts
por: Sambathkumar, Rangarajan, et al.
Publicado: (2016)

MicroRNA‐124a inhibits endoderm lineage commitment by targeting Sox17 and Gata6 in mouse embryonic stem cells
por: Liew, Lee Chuen, et al.
Publicado: (2019)

Hydrocortisone Promotes Differentiation of Mouse Embryonic Stem Cell-Derived Definitive Endoderm toward Lung Alveolar Epithelial Cells
por: Mokhber Dezfouli, Mohammad Reza, et al.
Publicado: (2019)

Endogenous suppression of WNT signalling in human embryonic stem cells leads to low differentiation propensity towards definitive endoderm
por: Dziedzicka, Dominika, et al.
Publicado: (2021)

Hydrocortisone Promotes Differentiation of Mouse Embryonic Stem Cell-Derived Definitive Endoderm toward Lung Alveolar Epithelial Cells
por: Mokhber Dezfouli, Mohammad Reza, et al.
Publicado: (2021)

Effects of low doses of methylmercury (MeHg) exposure on definitive endoderm cell differentiation in human embryonic stem cells
por: Li, Bai, et al.
Publicado: (2023)

Connexin 43 Functions as a Positive Regulator of Stem Cell Differentiation into Definitive Endoderm and Pancreatic Progenitors
por: Yang, Wendy, et al.
Publicado: (2019)

Argonaute 2 Is Required for Extra-embryonic Endoderm Differentiation of Mouse Embryonic Stem Cells
por: Ngondo, Richard Patryk, et al.
Publicado: (2018)

Protocol for siRNA-mediated TET1 knockdown during differentiation of human embryonic stem cells into definitive endoderm cells
por: Liufu, Zhongqi, et al.
Publicado: (2023)

Characteristics of the Endoderm: Embryonic and Extraembryonic in Mouse
por: Familari, Mary
Publicado: (2006)

Analysis of Regulatory Network Involved in Mechanical Induction of Embryonic Stem Cell Differentiation
por: Zhang, Xinan, et al.
Publicado: (2012)

An integer optimization algorithm for robust identification of non-linear gene regulatory networks
por: Chemmangattuvalappil, Nishanth, et al.
Publicado: (2012)

Polycomb enables primitive endoderm lineage priming in embryonic stem cells
por: Illingworth, Robert S, et al.
Publicado: (2016)

Tumor Suppressors and Endodermal Differentiation of P19 Embryonic Stem Cells
por: Kanungo, Jyotshna
Publicado: (2015)

Emergence and patterning dynamics of mouse-definitive endoderm
por: Pour, Maayan, et al.
Publicado: (2021)

A novel chemically directed route for the generation of definitive endoderm from human embryonic stem cells based on inhibition of GSK-3
por: Bone, Heather K., et al.
Publicado: (2011)

Mild electrical stimulation with heat shock guides differentiation of embryonic stem cells into Pdx1-expressing cells within the definitive endoderm
por: Koga, Tomoaki, et al.
Publicado: (2017)

Concerted cell divisions in embryonic visceral endoderm guide anterior visceral endoderm migration
por: Antonica, Francesco, et al.
Publicado: (2019)

Mitochondrial homeostasis regulates definitive endoderm differentiation of human pluripotent stem cells
por: Lv, Jing, et al.
Publicado: (2022)

Definitive Endodermal Cells Supply an in vitro Source of Mesenchymal Stem/Stromal Cells
por: Zhang, Yumeng, et al.
Publicado: (2023)

In silico discovery of small molecules for efficient stem cell differentiation into definitive endoderm
por: Novakovsky, Gherman, et al.
Publicado: (2023)

Early In Vitro Differentiation of Mouse Definitive Endoderm Is Not Correlated with Progressive Maturation of Nuclear DNA Methylation Patterns
por: Tajbakhsh, Jian, et al.
Publicado: (2011)

Modulation of the Pentose Phosphate Pathway Induces Endodermal Differentiation in Embryonic Stem Cells
por: Manganelli, Genesia, et al.
Publicado: (2012)

Differentiation of Mouse Embryonic Stem Cells into Endoderm without Embryoid Body Formation
por: Kim, Peter T. W., et al.
Publicado: (2010)

Mga safeguards embryonic stem cells from acquiring extraembryonic endoderm fates
por: Qin, Jinzhong, et al.
Publicado: (2021)

Insulin-Producing Cells Derived from Human Embryonic Stem Cells: Comparison of Definitive Endoderm- and Nestin-Positive Progenitor-Based Differentiation Strategies
por: Wei, Rui, et al.
Publicado: (2013)

DMSO Efficiently Down Regulates Pluripotency Genes in Human Embryonic Stem Cells during Definitive Endoderm Derivation and Increases the Proficiency of Hepatic Differentiation
por: Czysz, Katherine, et al.
Publicado: (2015)

Klf4 methylated by Prmt1 restrains the commitment of primitive endoderm
por: Zuo, Zhen-yu, et al.
Publicado: (2022)

PTF1a Activity in Enriched Posterior Foregut Endoderm, but Not Definitive Endoderm, Leads to Enhanced Pancreatic Differentiation in an In Vitro Mouse ESC-Based Model
por: Nair, Gopika G., et al.
Publicado: (2016)

Mesendogen, a novel inhibitor of TRPM6, promotes mesoderm and definitive endoderm differentiation of human embryonic stem cells through alteration of magnesium homeostasis
por: Geng, Yijie, et al.
Publicado: (2015)

MicroRNA Expression Patterns and Function in Endodermal Differentiation of Human Embryonic Stem Cells
por: Tzur, Galit, et al.
Publicado: (2008)

STELLA Facilitates Differentiation of Germ Cell and Endodermal Lineages of Human Embryonic Stem Cells
por: Wongtrakoongate, Patompon, et al.
Publicado: (2013)

Regulation of endodermal differentiation of human embryonic stem cells through integrin-ECM interactions
por: Brafman, D A, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_k01l2k048fb71j3q25i3hbeo0q