Active Trafficking of Alpha 1 Antitrypsin across the Lung Endothelium

The homeostatic lung protective effects of alpha-1 antitrypsin (A1AT) may require the transport of circulating proteinase inhibitor across an intact lung endothelial barrier. We hypothesized that uninjured pulmonary endothelial cells transport A1AT to lung epithelial cells. Purified human A1AT was r...

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Detalles Bibliográficos
Autores principales: Lockett, Angelia D., Brown, Mary Beth, Santos-Falcon, Nieves, Rush, Natalia I., Oueini, Houssam, Oberle, Amber J., Bolanis, Esther, Fragoso, Miryam A., Petrusca, Daniela N., Serban, Karina A., Schweitzer, Kelly S., Presson Jr., Robert G., Campos, Michael, Petrache, Irina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3990572/
https://www.ncbi.nlm.nih.gov/pubmed/24743137
http://dx.doi.org/10.1371/journal.pone.0093979

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