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Identification of cis-Acting Elements and Splicing Factors Involved in the Regulation of BIM Pre-mRNA Splicing

Aberrant changes in the expression of the pro-apoptotic protein, BCL-2-like 11 (BIM), can result in either impaired or excessive apoptosis, which can contribute to tumorigenesis and degenerative disorders, respectively. Altering BIM pre-mRNA splicing is an attractive approach to modulate apoptosis b...

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Detalles Bibliográficos
Autores principales:	Juan, Wen Chun, Roca, Xavier, Ong, S. Tiong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3990581/ https://www.ncbi.nlm.nih.gov/pubmed/24743263 http://dx.doi.org/10.1371/journal.pone.0095210

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