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Connecting the Dots: Potential of Data Integration to Identify Regulatory SNPs in Late-Onset Alzheimer's Disease GWAS Findings

Late-onset Alzheimer's disease (LOAD) is a multifactorial disorder with over twenty loci associated with disease risk. Given the number of genome-wide significant variants that fall outside of coding regions, it is possible that some of these variants alter some function of gene expression rath...

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Detalles Bibliográficos
Autores principales:	Rosenthal, Samantha L., Barmada, M. Michael, Wang, Xingbin, Demirci, F. Yesim, Kamboh, M. Ilyas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3990600/ https://www.ncbi.nlm.nih.gov/pubmed/24743338 http://dx.doi.org/10.1371/journal.pone.0095152

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