Cargando…

Intratumoral CD8(+) Cytotoxic Lymphocyte Is a Favorable Prognostic Marker in Node-Negative Breast Cancer

BACKGROUND: The prognostic effect of tumor infiltrating CD8(+) cytotoxic lymphocytes (CTLs) in breast cancer is controversial. We analyzed the association between CD8(+) CTLs and survival of untreated node-negative breast cancer patients. MATERIAL AND METHODS: CD8(+) CTLs infiltrate was evaluated by...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Zonglin, Chen, Xianyu, Zhou, Enxiang, Chen, Ganlong, Qian, Ke, Wu, Xia, Miao, Xiongying, Tang, Zhonghua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3990637/ https://www.ncbi.nlm.nih.gov/pubmed/24743335 http://dx.doi.org/10.1371/journal.pone.0095475

Ejemplares similares

Intratumoral Leptotrichia is a novel microbial marker for favorable clinical outcomes in head and neck cancer patients
por: Yu, Shuting, et al.
Publicado: (2023)

Intraepithelial Attack Rather than Intratumorally Infiltration of CD8+T Lymphocytes is a Favorable Prognostic Indicator in Pancreatic Ductal Adenocarcinoma
por: Zhang, J., et al.
Publicado: (2017)

Spatial and Quantitative Analysis of Tumor-Associated Macrophages: Intratumoral CD163-/PD-L1+ TAMs as a Marker of Favorable Clinical Outcomes in Triple-Negative Breast Cancer
por: Shinohara, Hajime, et al.
Publicado: (2022)

Intratumoral CXCR5(+)CD8(+)T associates with favorable clinical outcomes and immunogenic contexture in gastric cancer
por: Wang, Jieti, et al.
Publicado: (2021)

Immune-Activated Regional Lymph Nodes Predict Favorable Survival in Early-Stage Triple-Negative Breast Cancer
por: Chen, Yi-Yu, et al.
Publicado: (2020)

Sentinel Lymph Node Biopsy Was Associated With Favorable Survival Outcomes For Patients With Clinically Node-Negative Asian Melanoma
por: Chang, John Wen-Cheng, et al.
Publicado: (2019)

Intratumoral CD4(+) T Cells Mediate Anti-tumor Cytotoxicity in Human Bladder Cancer
por: Oh, David Y., et al.
Publicado: (2020)

Presence of lymphocytic infiltrate cytotoxic T lymphocyte CD3(+), CD8(+), and immunoscore as prognostic marker in patients after radical cystectomy
por: Yu, Alice, et al.
Publicado: (2018)

Intratumoral Cytotoxic T-Lymphocyte Density and PD-L1 Expression Are Prognostic Biomarkers for Patients with Colorectal Cancer
por: Calik, Ilknur, et al.
Publicado: (2019)

Prognostic implications of intratumoral CD103(+) tumor-infiltrating lymphocytes in pulmonary squamous cell carcinoma
por: Koh, Jaemoon, et al.
Publicado: (2017)

Intratumoral, rather than stromal, CD8+ T cells could be a potential negative prognostic marker in invasive breast cancer patients()()
por: Catacchio, Ivana, et al.
Publicado: (2019)

Soluble cytotoxic T-lymphocyte antigen 4: a favorable predictor in malignant tumors after therapy
por: Liu, Qiqi, et al.
Publicado: (2017)

Metabolic insufficiency underlies intratumoral cytotoxic T cell dysfunction
por: Gupta, Tushar, et al.
Publicado: (2015)

Intratumoral tertiary lymphoid structure (TLS) maturation is influenced by draining lymph nodes of lung cancer
por: He, Miao, et al.
Publicado: (2023)

Intravenous injection of a modified vaccinia ankara virus induces intratumoral CD8+ lymphocyte infiltration favoring tumor control in an orthotopic tumor model upon combinatorial treatment with a TLR9 agonist
por: Fend, Laetitia, et al.
Publicado: (2014)

Enhanced intratumoral expression of RNF2 is a favorable prognostic factor for patients with cutaneous melanoma?
por: Kuźbicki, Łukasz, et al.
Publicado: (2018)

Role of CD8 in Aberrant Function of Cytotoxic T Lymphocytes
por: Kessler, Benedikt, et al.
Publicado: (1997)

CRTAM determines the CD4(+) cytotoxic T lymphocyte lineage
por: Takeuchi, Arata, et al.
Publicado: (2016)

Prevalence of CD8(+) cytotoxic lymphocytes in human neoplasms
por: Blessin, Niclas C., et al.
Publicado: (2020)

Increasing negative lymph node count predicts favorable OS and DSS in breast cancer with different lymph node-positive subgroups
por: Zhao, Xin, et al.
Publicado: (2018)

Laser Additive Manufacturing of Anti-Tetrachiral Endovascular Stents with Negative Poisson’s Ratio and Favorable Cytocompatibility
por: Chen, Ke, et al.
Publicado: (2022)

Rapamycin improves Graves’ orbitopathy by suppressing CD4(+) cytotoxic T lymphocytes
por: Zhang, Meng, et al.
Publicado: (2023)

CD9 expression as a favorable prognostic marker for patients with malignant mesothelioma
por: AMATYA, VISHWA JEET, et al.
Publicado: (2012)

Tumor-Infiltrating CD4+ Lymphocytes Predict a Favorable Survival in Patients with Operable Esophageal Squamous Cell Carcinoma
por: Chen, Kaiyan, et al.
Publicado: (2017)

CD8(+ )lymphocyte infiltration is an independent favorable prognostic indicator in basal-like breast cancer
por: Liu, Shuzhen, et al.
Publicado: (2012)

Direct activation of CD8+ cytotoxic T lymphocytes by dendritic cells
Publicado: (1987)

Degranulation Response in Cytotoxic Rat Lymphocytes Measured with a Novel CD107a Antibody
por: Sudworth, Amanda, et al.
Publicado: (2016)

CXCR6 is required for antitumor efficacy of intratumoral CD8(+) T cell
por: Wang, Binglin, et al.
Publicado: (2021)

Effects of Interleukin‐12 on the Induction of Cytotoxic T Lymphocytes from the Regional Lymph Node Lymphocytes of Patients with Lung Adenocarcinoma
por: Hanagiri, Takeshi, et al.
Publicado: (1998)

Infiltration by Intratumor and Stromal CD8 and CD68 in Cervical Cancer
por: Dimitrova, Polina, et al.
Publicado: (2023)

Intratumoral SIRPα-deficient macrophages activate tumor antigen-specific cytotoxic T cells under radiotherapy
por: Bian, Zhen, et al.
Publicado: (2021)

Clinicopathological significance of intratumoral and peritumoral lymphocytes and lymphocyte score based on the histologic subtypes of cutaneous melanoma
por: Park, Cheol Keun, et al.
Publicado: (2017)

CD74 and intratumoral immune response in breast cancer
por: Wang, Zhi-Qiang, et al.
Publicado: (2016)

Cd40-Independent Pathways of T Cell Help for Priming of Cd8(+) Cytotoxic T Lymphocytes
por: Lu, Zhengbin, et al.
Publicado: (2000)

Intratumoral peptide injection enhances tumor cell antigenicity recognized by cytotoxic T lymphocytes: a potential option for improvement in antigen-specific cancer immunotherapy
por: Nobuoka, Daisuke, et al.
Publicado: (2012)

Location, location, location: CD103 demarcates intraepithelial, prognostically favorable CD8(+) tumor-infiltrating lymphocytes in ovarian cancer
por: Webb, John R, et al.
Publicado: (2014)

Current Treatments for Breast Cancer-Related Lymphoedema: A Systematic Review
por: Li, Lun, et al.
Publicado: (2016)

Tumor-infiltrating CD45RO(+) Memory T Lymphocytes Predict Favorable Clinical Outcome in Solid Tumors
por: Hu, Guoming, et al.
Publicado: (2017)

CD103(+) tumor-infiltrating lymphocytes predict favorable prognosis in patients with esophageal squamous cell carcinoma
por: Chu, Yifan, et al.
Publicado: (2019)

Androgen receptor expression identifies patient with favorable outcome in operable triple negative breast cancer
por: Hu, Xiao-Qing, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_j0skbo2j0rfjrv2ltmok5jbjcf