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Generation and Characterization of a Mouse Model Harboring the Exon-3 Deletion in the Cardiac Ryanodine Receptor

A large genomic deletion in human cardiac ryanodine receptor (RYR2) gene has been detected in a number of unrelated families with various clinical phenotypes, including catecholaminergic polymorphic ventricular tachycardia (CPVT). This genomic deletion results in an in-frame deletion of exon-3 (Ex3-...

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Detalles Bibliográficos
Autores principales:	Liu, Yingjie, Wang, Ruiwu, Sun, Bo, Mi, Tao, Zhang, Jingqun, Mu, Yongxin, Chen, Ju, Bround, Michael J., Johnson, James D., Gillis, Anne M., Chen, S. R. Wayne
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3990712/ https://www.ncbi.nlm.nih.gov/pubmed/24743769 http://dx.doi.org/10.1371/journal.pone.0095615

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