Cargando…
Modified STING-activating cyclic dinucleotide derivatives significantly enhance the anti-tumor activity of therapeutic vaccines
Autores principales: | Leong, Meredith, Kanne, David, Glickman, Laura, Lemmens, Edward, Lauer, Peter, Metchette, Ken, Burdette, Dara, Diner, Elie, Fu, Juan, Soares, Kevin, Brockstedt, Dirk, Portnoy, Daniel, Vance, Russell, Kim, Young, Jaffee, Elizabeth, Pardoll, Drew, Dubensky, Thomas |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3990975/ http://dx.doi.org/10.1186/2051-1426-1-S1-O20 |
Ejemplares similares
-
Direct activation of STING in the tumor microenvironment with synthetic cyclic dinucleotide derivatives leads to potent and systemic tumor-specific immunity
por: Corrales, Leticia, et al.
Publicado: (2014) -
Cyclic dinucleotides (CDNs) reversed T cells tolerance in anti-tumor immunotherapy
por: Fu, Juan, et al.
Publicado: (2015) -
Direct activation of STING in the tumor microenvironment partially overcomes immune tolerance in neu-N transgenic mice
por: Foote, Jeremy, et al.
Publicado: (2015) -
Cyclic dinucleotides (CDNs) anti-tumors response by activating DC and NK cell crosstalk
por: Fu, Juan, et al.
Publicado: (2014) -
STING cyclic dinucleotide sensing originated in bacteria
por: Morehouse, Benjamin R., et al.
Publicado: (2020)