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Inclusion cylinder method for aortic valve replacement utilising the Ross operation in adults with predominant aortic stenosis – 99% freedom from re-operation on the aortic valve at 15 years

Background: To report our experience with the Ross operation in patients with predominant aortic stenosis (AS) using an inclusion cylinder (IC) method. Methods: Out of 324 adults undergoing a Ross operation, 204 patients of mean age of 41.3 years (limits 16–62) underwent this procedure for either AS...

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Autores principales: Skillington, Peter D., Mokhles, M. Mostafa, Wilson, William, Grigg, Leeanne, Larobina, Marco, O'Keefe, Michael, Takkenberg, Johanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bloomsbury Qatar Foundation Journals 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3991211/
https://www.ncbi.nlm.nih.gov/pubmed/24749112
http://dx.doi.org/10.5339/gcsp.2013.46
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author Skillington, Peter D.
Mokhles, M. Mostafa
Wilson, William
Grigg, Leeanne
Larobina, Marco
O'Keefe, Michael
Takkenberg, Johanna
author_facet Skillington, Peter D.
Mokhles, M. Mostafa
Wilson, William
Grigg, Leeanne
Larobina, Marco
O'Keefe, Michael
Takkenberg, Johanna
author_sort Skillington, Peter D.
collection PubMed
description Background: To report our experience with the Ross operation in patients with predominant aortic stenosis (AS) using an inclusion cylinder (IC) method. Methods: Out of 324 adults undergoing a Ross operation, 204 patients of mean age of 41.3 years (limits 16–62) underwent this procedure for either AS or mixed AS and regurgitation (AS/AR) between October, 1992 and February, 2012, implanting the PA with an IC method. Clinical follow up and serial echo data for this group is 97% complete with late mortality follow up 99% complete. Results: There has been zero (0%) early mortality, and late survival at 15 years is 98% (96%, 100%). Only one re-operation on the aortic valve for progressive aortic regurgitation (AR) has been required with freedom from re-operation on the aortic valve at 15 years being 99% (96%, 100%). The freedom from all re-operations on the aortic and pulmonary valves at 15 years is 97% (94%, 100%). Echo analysis at the most recent study shows that 98% have nil, trivial or mild AR. Aortic root size has remained stable, shown by long-term (15 year) echo follow up. Conclusions: In an experience spanning 19 years, the Ross operation used for predominant AS using the IC method described, results in 99% freedom from re-operation on the aortic valve at 15 years, better than any other tissue or mechanical valve. For adults under 65 years without significant co-morbidities who present with predominant AS, the pulmonary autograft inserted with this technique gives excellent results.
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spelling pubmed-39912112014-04-18 Inclusion cylinder method for aortic valve replacement utilising the Ross operation in adults with predominant aortic stenosis – 99% freedom from re-operation on the aortic valve at 15 years Skillington, Peter D. Mokhles, M. Mostafa Wilson, William Grigg, Leeanne Larobina, Marco O'Keefe, Michael Takkenberg, Johanna Glob Cardiol Sci Pract Research Article Background: To report our experience with the Ross operation in patients with predominant aortic stenosis (AS) using an inclusion cylinder (IC) method. Methods: Out of 324 adults undergoing a Ross operation, 204 patients of mean age of 41.3 years (limits 16–62) underwent this procedure for either AS or mixed AS and regurgitation (AS/AR) between October, 1992 and February, 2012, implanting the PA with an IC method. Clinical follow up and serial echo data for this group is 97% complete with late mortality follow up 99% complete. Results: There has been zero (0%) early mortality, and late survival at 15 years is 98% (96%, 100%). Only one re-operation on the aortic valve for progressive aortic regurgitation (AR) has been required with freedom from re-operation on the aortic valve at 15 years being 99% (96%, 100%). The freedom from all re-operations on the aortic and pulmonary valves at 15 years is 97% (94%, 100%). Echo analysis at the most recent study shows that 98% have nil, trivial or mild AR. Aortic root size has remained stable, shown by long-term (15 year) echo follow up. Conclusions: In an experience spanning 19 years, the Ross operation used for predominant AS using the IC method described, results in 99% freedom from re-operation on the aortic valve at 15 years, better than any other tissue or mechanical valve. For adults under 65 years without significant co-morbidities who present with predominant AS, the pulmonary autograft inserted with this technique gives excellent results. Bloomsbury Qatar Foundation Journals 2013-12-30 /pmc/articles/PMC3991211/ /pubmed/24749112 http://dx.doi.org/10.5339/gcsp.2013.46 Text en © 2013 Skillington, Mokhles, Wilson, Grigg, Larobina, O'Keefe, Takkenberg, licensee Bloomsbury Qatar Foundation Journals. This is an open access article distributed under the terms of the Creative Commons Attribution license CC BY 3.0, which permits unrestricted use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Skillington, Peter D.
Mokhles, M. Mostafa
Wilson, William
Grigg, Leeanne
Larobina, Marco
O'Keefe, Michael
Takkenberg, Johanna
Inclusion cylinder method for aortic valve replacement utilising the Ross operation in adults with predominant aortic stenosis – 99% freedom from re-operation on the aortic valve at 15 years
title Inclusion cylinder method for aortic valve replacement utilising the Ross operation in adults with predominant aortic stenosis – 99% freedom from re-operation on the aortic valve at 15 years
title_full Inclusion cylinder method for aortic valve replacement utilising the Ross operation in adults with predominant aortic stenosis – 99% freedom from re-operation on the aortic valve at 15 years
title_fullStr Inclusion cylinder method for aortic valve replacement utilising the Ross operation in adults with predominant aortic stenosis – 99% freedom from re-operation on the aortic valve at 15 years
title_full_unstemmed Inclusion cylinder method for aortic valve replacement utilising the Ross operation in adults with predominant aortic stenosis – 99% freedom from re-operation on the aortic valve at 15 years
title_short Inclusion cylinder method for aortic valve replacement utilising the Ross operation in adults with predominant aortic stenosis – 99% freedom from re-operation on the aortic valve at 15 years
title_sort inclusion cylinder method for aortic valve replacement utilising the ross operation in adults with predominant aortic stenosis – 99% freedom from re-operation on the aortic valve at 15 years
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3991211/
https://www.ncbi.nlm.nih.gov/pubmed/24749112
http://dx.doi.org/10.5339/gcsp.2013.46
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