Cargando…

A novel peptide therapeutic targeting PD1 immune checkpoint with equipotent antagonism of both ligands and a potential for better management of immune-related adverse events

Detalles Bibliográficos
Autores principales:	Sasikumar, Pottayil, Shrimali, Rajeev, Adurthi, Sreenivas, Ramachandra, Raghuveer, Satyam, Leena, Dhudashiya, Amit, Samiulla, Dodheri, Sunilkumar, K B, Ramachandra, Murali
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Oral Presentation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3991264/ http://dx.doi.org/10.1186/2051-1426-1-S1-O24

Ejemplares similares

PD-1 derived CA-170 is an oral immune checkpoint inhibitor that exhibits preclinical anti-tumor efficacy
por: Sasikumar, Pottayil G., et al.
Publicado: (2021)

Small Molecule Agents Targeting PD-1 Checkpoint Pathway for Cancer Immunotherapy: Mechanisms of Action and Other Considerations for Their Advanced Development
por: Sasikumar, Pottayil G., et al.
Publicado: (2022)

Discovery of indole tetrafluorophenoxymethylketone-based potent novel small molecule inhibitors of caspase-3
por: Samiulla, Dodheri Syed, et al.
Publicado: (2012)

MON-365 Immune Checkpoint Inhibitors: Endocrinopathies and Severe Electrolyte Abnormalities
por: El Mais, Rania, et al.
Publicado: (2019)

Comparison of equipotent doses of rocuronium and vecuronium
por: Parasa, Mrunalini, et al.
Publicado: (2015)

An adenovirus prime/plasmid boost strategy for induction of equipotent immune responses to two dengue virus serotypes
por: Khanam, Saima, et al.
Publicado: (2007)

Abundant and equipotent founder cells establish and maintain acute lymphoblastic leukaemia
por: Elder, A, et al.
Publicado: (2017)

A cumulative analysis of odontogenic cysts from major dental institutions of Bangalore city: A study of 252 cases
por: Ramachandra, Prashanth, et al.
Publicado: (2011)

Novel CDK12/13 Inhibitors AU-15506 and AU-16770 Are Potent Anti-Cancer Agents in EGFR Mutant Lung Adenocarcinoma with and without Osimertinib Resistance
por: Maity, Tapan K., et al.
Publicado: (2023)

Equipotency of lacosamide to levetiracetam in new onset focal epilepsy: A randomized controlled trial
por: Jaiswal, Binaya Kumar, et al.
Publicado: (2023)

Nano-Chemotherapy synergize with immune checkpoint inhibitor- A better option?
por: Qian, Xinye, et al.
Publicado: (2022)

Immune checkpoint therapy in colorectal cancer: is first better than last?
por: Kaneko, Yui, et al.
Publicado: (2023)

A novel retinoic acid receptor-γ agonist antagonizes immune checkpoint resistance in lung cancers by altering the tumor immune microenvironment
por: Wei, Cheng-Hsin, et al.
Publicado: (2023)

Idoxifene is equipotent to tamoxifen in inhibiting mammary carcinogenesis but forms lower levels of hepatic DNA adducts.
por: Pace, P., et al.
Publicado: (1997)

Early CD8 T-cell memory precursors and terminal effectors exhibit equipotent in vivo degranulation
por: Yuzefpolskiy, Yevgeniy, et al.
Publicado: (2015)

Mirror‐Image Packing Provides a Molecular Basis for the Nanomolar Equipotency of Enantiomers of an Experimental Herbicide
por: Bisson, Claudine, et al.
Publicado: (2016)

Mouse Spermatogenic Stem Cells Continually Interconvert between Equipotent Singly Isolated and Syncytial States
por: Hara, Kenshiro, et al.
Publicado: (2014)

Coherence of Visual-Evoked Gamma Oscillations Is Disrupted by Propofol but Preserved Under Equipotent Doses of Isoflurane
por: Aggarwal, Adeeti, et al.
Publicado: (2019)

Rigidity of loop 1 contributes to equipotency of globular and ribbon isomers of α-conotoxin AusIA
por: Ho, Thao N. T., et al.
Publicado: (2021)

Effect of equipotent doses of propofol and sevoflurane on endoplasmic reticulum stress during breast cancer surgery
por: Oh, Chung-Sik, et al.
Publicado: (2022)

Tumor mutation burden for predicting immune checkpoint blockade response: the more, the better
por: Zheng, Ming
Publicado: (2022)

Combination of immune-checkpoint inhibitors and targeted therapies for melanoma therapy: The more, the better?
por: Haist, Maximilian, et al.
Publicado: (2023)

Rotavirus Antagonism of the Innate Immune Response
por: Arnold, Michelle M., et al.
Publicado: (2009)

An Allosteric Modulator of HIV-1 Protease Shows Equipotent Inhibition of Wild-Type and Drug-Resistant Proteases
por: Ung, Peter M.-U., et al.
Publicado: (2014)

Response to a letter to the editor: a better understanding of Immune Checkpoint Inhibitor-induced cholangitis for better management
por: Coukos, Alexander, et al.
Publicado: (2023)

Cloning and characterization of microRNAs from rainbow trout (Oncorhynchus mykiss): Their expression during early embryonic development
por: Ramachandra, Raghuveer K, et al.
Publicado: (2008)

Epidural anesthesia and post-operative analgesia for bilateral inguinal mesh hernioplasty: Comparison of equipotent doses of ropivacaine and bupivacaine
por: Korula, Sara, et al.
Publicado: (2011)

To Compare the Intravenous Bolus Dose of Propofol With an Equipotent Dose of Intravenous Thiopentone for the Facilitation of Laryngeal Mask Airway Insertion
por: Saloi, Dilip K, et al.
Publicado: (2022)

Antagonism of Innate Immunity by Paramyxovirus Accessory Proteins
por: Chambers, Raychel, et al.
Publicado: (2009)

Human Metapneumovirus Antagonism of Innate Immune Responses
por: Kolli, Deepthi, et al.
Publicado: (2012)

Addiction systems antagonize bacterial adaptive immunity
por: van Sluijs, Lisa, et al.
Publicado: (2019)

Transnasal sphenopalatine ganglion block for the treatment of postdural puncture headache following spinal anesthesia
por: Channabasappa, Shivakumar M., et al.
Publicado: (2017)

Prevention of hypotension associated with the induction dose of propofol: A randomized controlled trial comparing equipotent doses of phenylephrine and ephedrine
por: Farhan, Muhammad, et al.
Publicado: (2015)

Estimation of Equipotent Doses for Anti‐Inflammatory Effects of Prednisolone and AZD9567, an Oral Selective Nonsteroidal Glucocorticoid Receptor Modulator
por: Almquist, Joachim, et al.
Publicado: (2020)

Equipotency of insulin glargine 300 and 100 U/mL with intravenous dosing but differential bioavailability with subcutaneous dosing in dogs
por: Werner, Ulrich, et al.
Publicado: (2020)

Comparison of equipotent doses of Ramosetron, Ondansetron, and sub-hypnotic dose of Propofol for prevention of postoperative nausea and vomiting in laparoscopic cholecystectomy
por: Acharya, Shilpa Amol, et al.
Publicado: (2021)

Sequential or Simultaneous Injection of Preformed Fibrils and AAV Overexpression of Alpha-Synuclein Are Equipotent in Producing Relevant Pathology and Behavioral Deficits
por: Negrini, Matilde, et al.
Publicado: (2022)

The side effects of immune checkpoint inhibitor therapy on the endocrine system
por: Goyal, Itivrita, et al.
Publicado: (2021)

Immune checkpoint inhibitors
por: Hui, Enfu
Publicado: (2019)

Immune checkpoint inhibitors
por: Kroemer, Guido, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_pkbm88iul47hlabk2t07oodg5n