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Rrp5 Binding at Multiple Sites Coordinates Pre-rRNA Processing and Assembly
In vivo UV crosslinking identified numerous preribosomal RNA (pre-rRNA) binding sites for the large, highly conserved ribosome synthesis factor Rrp5. Intramolecular complementation has shown that the C-terminal domain (CTD) of Rrp5 is required for pre-rRNA cleavage at sites A0–A2 on the pathway of 1...
Autores principales: | Lebaron, Simon, Segerstolpe, Åsa, French, Sarah L., Dudnakova, Tatiana, de lima Alves, Flavia, Granneman, Sander, Rappsilber, Juri, Beyer, Ann L., Wieslander, Lars, Tollervey, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3991325/ https://www.ncbi.nlm.nih.gov/pubmed/24239293 http://dx.doi.org/10.1016/j.molcel.2013.10.017 |
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