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Optimal Translational Termination Requires C4 Lysyl Hydroxylation of eRF1

Efficient stop codon recognition and peptidyl-tRNA hydrolysis are essential in order to terminate translational elongation and maintain protein sequence fidelity. Eukaryotic translational termination is mediated by a release factor complex that includes eukaryotic release factor 1 (eRF1) and eRF3. T...

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Detalles Bibliográficos
Autores principales:	Feng, Tianshu, Yamamoto, Atsushi, Wilkins, Sarah E., Sokolova, Elizaveta, Yates, Luke A., Münzel, Martin, Singh, Pooja, Hopkinson, Richard J., Fischer, Roman, Cockman, Matthew E., Shelley, Jake, Trudgian, David C., Schödel, Johannes, McCullagh, James S.O., Ge, Wei, Kessler, Benedikt M., Gilbert, Robert J., Frolova, Ludmila Y., Alkalaeva, Elena, Ratcliffe, Peter J., Schofield, Christopher J., Coleman, Mathew L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cell Press 2014
Materias:	Short Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3991326/ https://www.ncbi.nlm.nih.gov/pubmed/24486019 http://dx.doi.org/10.1016/j.molcel.2013.12.028

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