Cargando…

“First AID” for T cell adoptive transfer: TCR affinity maturation by somatic hypermutation

Detalles Bibliográficos
Autores principales:	Gozlan, Yosi M, Tzehoval, Esther, Eisenbach, Lea
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Poster Presentation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3991362/ http://dx.doi.org/10.1186/2051-1426-1-S1-P11

Ejemplares similares

Avidity optimization of a MAGE‐A1‐specific TCR with somatic hypermutation
por: Bassan, David, et al.
Publicado: (2021)

Intricate targeting of immunoglobulin somatic hypermutation maximizes the efficiency of affinity maturation
por: Zheng, Nai-Ying, et al.
Publicado: (2005)

Attracting AID to targets of somatic hypermutation
por: Tanaka, Atsushi, et al.
Publicado: (2010)

AID function in somatic hypermutation and class switch recombination: AID function in somatic hypermutation and class switch recombination
por: Yu, Kefei
Publicado: (2022)

P71. Adoptive transfer of TCR gene-transduced lymphocytes targeting MAGE-A4 for refractory esophageal cancer
por: Shiku, H, et al.
Publicado: (2014)

Immunoglobulin somatic hypermutation in a defined biochemical system recapitulates affinity maturation and permits antibody optimization
por: Jeong, Soo Lim, et al.
Publicado: (2022)

UNG shapes the specificity of AID-induced somatic hypermutation
por: Pérez-Durán, Pablo, et al.
Publicado: (2012)

Restriction of AID activity and somatic hypermutation by PARP-1
por: Tepper, Sandra, et al.
Publicado: (2019)

Antibody lineages with evidence of somatic hypermutation persisting for >4 years in a South African subject with broad neutralizing activity
por: Moody, M, et al.
Publicado: (2012)

Enhancers Improve the AID-Induced Hypermutation in Episomal Vector for Antibody Affinity Maturation in Mammalian Cell Display
por: Chen, Chuan, et al.
Publicado: (2018)

P20-20 LB. Indels in V4 share sequence features with insertions and deletions during somatic hypermutation of immunoglobulins
por: Guglietta, S, et al.
Publicado: (2009)

Adoptive immunotherapy with engineered T cells expressing and HLA-A2 restricted affinity-enhanced TCR for LAGE-1 and NY-ESO-1 in patients with multiple myeloma following auto-SCT
por: Rapoport, Aaron P, et al.
Publicado: (2013)

Production of LacZ Inducible T Cell Hybridoma Specific for Human and Mouse gp100(25–33) Peptides
por: Cafri, Gal, et al.
Publicado: (2013)

Adoptively transferred tumor-infiltrating T cells target somatic cancer mutations in a human papillomavirus+ cancer patient with complete tumor regression
por: Stevanović, Sanja, et al.
Publicado: (2015)

Tandem Substitutions in Somatic Hypermutation
por: Sepúlveda-Yáñez, Julieta H., et al.
Publicado: (2022)

Activation-induced Deaminase (AID)-directed Hypermutation in the Immunoglobulin Sμ Region: Implication of AID Involvement in a Common Step of Class Switch Recombination and Somatic Hypermutation
por: Nagaoka, Hitoshi, et al.
Publicado: (2002)

Altering the spectrum of immunoglobulin V gene somatic hypermutation by modifying the active site of AID
por: Wang, Meng, et al.
Publicado: (2010)

Preclinical safety testing of an affinity-optimised MAGE-A10 T cell receptor for adoptive T cell therapy
por: Gerry, Andrew, et al.
Publicado: (2015)

Adoptive transfer of tumor infiltrating lymphocytes for metastatic cervical cancer
por: Hinrichs, Christian S, et al.
Publicado: (2013)

Lymph act, TCR αβ, TCR γδ cells in peripheral blood in children with juvenile idiopathic arthritis
por: Mazur-Zielinska, H
Publicado: (2008)

Affinity maturation pathway of an anti-MPER neutralizing mAb, CAP206-CH12
por: Tumba, NL, et al.
Publicado: (2012)

Identifying protein–protein interactions in somatic hypermutation
por: Goodman, Myron F., et al.
Publicado: (2005)

Recurrent targets of aberrant somatic hypermutation in lymphoma
por: Khodabakhshi, Alireza Hadj, et al.
Publicado: (2012)

Changes in RNA polymerase II progression influence somatic hypermutation of Ig-related genes by AID
por: Kodgire, Prashant, et al.
Publicado: (2013)

High Affinity Humanized Antibodies without Making Hybridomas; Immunization Paired with Mammalian Cell Display and In Vitro Somatic Hypermutation
por: McConnell, Audrey D., et al.
Publicado: (2012)

Human Immunodeficiency Virus Tat Protein Aids V Region Somatic Hypermutation in Human B Cells
por: Wang, Xiaohua, et al.
Publicado: (2018)

Characterization of the TCR V repertoire of piperacillin-specific T-cells
por: Al-Attar, Zaid, et al.
Publicado: (2014)

Optimizing engineered TCR T cell therapy for synovial sarcoma
por: D'Angelo, Sandra, et al.
Publicado: (2015)

Somatic hypermutation of an immunoglobulin mu heavy chain transgene
Publicado: (1993)

The Role of DNA Repair in Somatic Hypermutation of Immunoglobulin Genes
por: Kim, Nayun, et al.
Publicado: (1998)

Checkpoint kinase 1 negatively regulates somatic hypermutation
por: Frankenberger, Samantha, et al.
Publicado: (2014)

Ultradeep analysis of tumor heterogeneity in regions of somatic hypermutation
por: Spence, Janice M, et al.
Publicado: (2015)

Topologically Associated Domains Delineate Susceptibility to Somatic Hypermutation
por: Senigl, Filip, et al.
Publicado: (2019)

Anti-EGFR mAb cetuximab therapy increases T cell receptor (TCR) diversity in the peripheral blood and focuses TCR richness in the tumor microenvironment
por: Kansy, Benjamin A, et al.
Publicado: (2015)

In vivo persistence of adoptively transferred TCR gene-transduced lymphocytes with anti-tumor reactivity in patients with MAGE-A4 expressing esophageal cancer
por: Ikeda, Hiroaki, et al.
Publicado: (2013)

Skewing of the TCR V repertoire in SMX-NO specific T cell responses
por: Faulkner, Lee, et al.
Publicado: (2014)

Precision immunophenotyping by high-throughput TCR sequencing in human glioma
por: Sims, Jennifer, et al.
Publicado: (2015)

Affinity maturation of TCR-like antibodies using phage display guided by structural modeling
por: Frick, Rahel, et al.
Publicado: (2022)

Pre-T cell receptor for improved expansion of TCR alpha disrupted T cells
por: Galetto, Roman, et al.
Publicado: (2013)

Cish attenuates proximal TCR-signaling and CD8+ T cell immunity
por: Palmer, Douglas, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_3jsfdn3t8v22jn2o92qka6pcn0