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Basal and inducible anti-inflammatory epoxygenase activity in endothelial cells

The roles of CYP lipid-metabolizing pathways in endothelial cells are poorly understood. Human endothelial cells expressed CYP2J2 and soluble epoxide hydrolase (sEH) mRNA and protein. The TLR-4 agonist LPS (1 μg/ml; 24 h) induced CYP2J2 but not sEH mRNA and protein. LC–MS/MS analysis of the stable c...

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Detalles Bibliográficos
Autores principales:	Askari, Ara A., Thomson, Scott, Edin, Matthew L., Lih, Fred B., Zeldin, Darryl C., Bishop-Bailey, David
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Academic Press 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3991391/ https://www.ncbi.nlm.nih.gov/pubmed/24631907 http://dx.doi.org/10.1016/j.bbrc.2014.03.020

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