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Stable overexpression of miR-17 enhances recombinant protein production of CHO cells()

miRNAs negatively regulate gene expression at post-transcriptional level, and consequently play an important role in the control of many cellular pathways. The use of miRNAs to engineer Chinese hamster ovary (CHO) cells is an emerging strategy to improve recombinant protein production. Here, we desc...

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Detalles Bibliográficos
Autores principales:	Jadhav, Vaibhav, Hackl, Matthias, Klanert, Gerald, Hernandez Bort, Juan A., Kunert, Renate, Grillari, Johannes, Borth, Nicole
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Science Publishers 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3991393/ https://www.ncbi.nlm.nih.gov/pubmed/24518263 http://dx.doi.org/10.1016/j.jbiotec.2014.01.032

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