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Facts and myths in serological screening of ART couples

Serological screening of couples attending for ART therapy is now common practice. The frequency of such screening is a topic of debate as few publications have addressed this question. Emerging evidence shows that the ART population has similar prevalence of infectious diseases compared with the ge...

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Autor principal: Mocanu, E.V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Universa Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3991400/
https://www.ncbi.nlm.nih.gov/pubmed/24753908
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author Mocanu, E.V.
author_facet Mocanu, E.V.
author_sort Mocanu, E.V.
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description Serological screening of couples attending for ART therapy is now common practice. The frequency of such screening is a topic of debate as few publications have addressed this question. Emerging evidence shows that the ART population has similar prevalence of infectious diseases compared with the general EU population. The need to pursue repeat screening is mainly related to the risk of seroconversion in this highly selected population. The evidence presented here shows that seroconversion among cohabitating ART couples is negligible. Even if a theoretical risk of seroconversion during therapy exists, with correct laboratory practice the risk of cross-contamination is negligible as laboratory processing eliminates the infective risk. As such ART laboratory processing of contaminated samples becomes an indication rather than a risk. To strengthen the evidence it is recommended that data on prevalence and incidence should be prospectively collected by all ART units.
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spelling pubmed-39914002014-04-21 Facts and myths in serological screening of ART couples Mocanu, E.V. Facts Views Vis Obgyn Opinion Paper Serological screening of couples attending for ART therapy is now common practice. The frequency of such screening is a topic of debate as few publications have addressed this question. Emerging evidence shows that the ART population has similar prevalence of infectious diseases compared with the general EU population. The need to pursue repeat screening is mainly related to the risk of seroconversion in this highly selected population. The evidence presented here shows that seroconversion among cohabitating ART couples is negligible. Even if a theoretical risk of seroconversion during therapy exists, with correct laboratory practice the risk of cross-contamination is negligible as laboratory processing eliminates the infective risk. As such ART laboratory processing of contaminated samples becomes an indication rather than a risk. To strengthen the evidence it is recommended that data on prevalence and incidence should be prospectively collected by all ART units. Universa Press 2012 /pmc/articles/PMC3991400/ /pubmed/24753908 Text en Copyright: © 2012 Facts, Views & Vision http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Opinion Paper
Mocanu, E.V.
Facts and myths in serological screening of ART couples
title Facts and myths in serological screening of ART couples
title_full Facts and myths in serological screening of ART couples
title_fullStr Facts and myths in serological screening of ART couples
title_full_unstemmed Facts and myths in serological screening of ART couples
title_short Facts and myths in serological screening of ART couples
title_sort facts and myths in serological screening of art couples
topic Opinion Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3991400/
https://www.ncbi.nlm.nih.gov/pubmed/24753908
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