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Postterm pregnancy

Postterm pregnancy is a pregnancy that extends to 42 weeks of gestation or beyond. Fetal, neonatal and maternal complications associated with this condition have always been underestimated. It is not well understood why some women become postterm although in obesity, hormonal and genetic factors hav...

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Detalles Bibliográficos
Autores principales: Galal, M., Symonds, I., Murray, H., Petraglia, F., Smith, R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Universa Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3991404/
https://www.ncbi.nlm.nih.gov/pubmed/24753906
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author Galal, M.
Symonds, I.
Murray, H.
Petraglia, F.
Smith, R.
author_facet Galal, M.
Symonds, I.
Murray, H.
Petraglia, F.
Smith, R.
author_sort Galal, M.
collection PubMed
description Postterm pregnancy is a pregnancy that extends to 42 weeks of gestation or beyond. Fetal, neonatal and maternal complications associated with this condition have always been underestimated. It is not well understood why some women become postterm although in obesity, hormonal and genetic factors have been implicated. The management of postterm pregnancy constitutes a challenge to clinicians; knowing who to induce, who will respond to induction and who will require a caesarean section (CS). The current definition and management of postterm pregnancy have been challenged in several studies as the emerging evidence demonstrates that the incidence of complications associated with postterm pregnancy also increase prior to 42 weeks of gestation. For example the incidence of stillbirth increases from 39 weeks onwards with a sharp rise after 40 weeks of gestation. Induction of labour before 42 weeks of gestation has the potential to prevent these complications; however, both patients and clinicians alike are concerned about risks associated with induction of labour such as failure of induction and increases in CS rates. There is a strong body of evidence however that demonstrates that induction of labour at term and prior to 42 weeks of gestation (particularly between 40 & 42 weeks) is associated with a reduction in perinatal complications without an associated increase in CS rates. It seems therefore that a policy of induction of labour at 41 weeks in postterm women could be beneficial with potential improvement in perinatal outcome and a reduction in maternal complications.
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spelling pubmed-39914042014-04-21 Postterm pregnancy Galal, M. Symonds, I. Murray, H. Petraglia, F. Smith, R. Facts Views Vis Obgyn Review Postterm pregnancy is a pregnancy that extends to 42 weeks of gestation or beyond. Fetal, neonatal and maternal complications associated with this condition have always been underestimated. It is not well understood why some women become postterm although in obesity, hormonal and genetic factors have been implicated. The management of postterm pregnancy constitutes a challenge to clinicians; knowing who to induce, who will respond to induction and who will require a caesarean section (CS). The current definition and management of postterm pregnancy have been challenged in several studies as the emerging evidence demonstrates that the incidence of complications associated with postterm pregnancy also increase prior to 42 weeks of gestation. For example the incidence of stillbirth increases from 39 weeks onwards with a sharp rise after 40 weeks of gestation. Induction of labour before 42 weeks of gestation has the potential to prevent these complications; however, both patients and clinicians alike are concerned about risks associated with induction of labour such as failure of induction and increases in CS rates. There is a strong body of evidence however that demonstrates that induction of labour at term and prior to 42 weeks of gestation (particularly between 40 & 42 weeks) is associated with a reduction in perinatal complications without an associated increase in CS rates. It seems therefore that a policy of induction of labour at 41 weeks in postterm women could be beneficial with potential improvement in perinatal outcome and a reduction in maternal complications. Universa Press 2012 /pmc/articles/PMC3991404/ /pubmed/24753906 Text en Copyright: © 2012 Facts, Views & Vision http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review
Galal, M.
Symonds, I.
Murray, H.
Petraglia, F.
Smith, R.
Postterm pregnancy
title Postterm pregnancy
title_full Postterm pregnancy
title_fullStr Postterm pregnancy
title_full_unstemmed Postterm pregnancy
title_short Postterm pregnancy
title_sort postterm pregnancy
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3991404/
https://www.ncbi.nlm.nih.gov/pubmed/24753906
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